Swinburn B, Ravussin E
Department of Community Health, School of Medicine, University of Auckland, New Zealand.
Am J Clin Nutr. 1993 May;57(5 Suppl):766S-770S; discussion 770S-771S. doi: 10.1093/ajcn/57.5.766S.
Under normal conditions, carbohydrate, protein, and alcohol are not converted to fat. Glycogen and protein stores are closely controlled, and increasing the intake of nonfat nutrients stimulates their oxidation rates proportionally. Thus, chronic imbalance between intake and oxidation of nonfat nutrients cannot lead to obesity. On the other hand, fat stores are not controlled and their capacity for expansion is enormous. Because an increase in fat intake does not stimulate fat oxidation, a positive fat balance results, which has the potential to become chronic. Obesity is therefore due to a long-standing positive fat balance, which may simply be due to a high-fat diet. The use of the fat-balance equation instead of the energy-balance equation adds another option for the treatment of obesity--that of changing the quality of the diet, ie, lowering the fat content.
在正常情况下,碳水化合物、蛋白质和酒精不会转化为脂肪。糖原和蛋白质储备受到严格控制,增加非脂肪营养素的摄入量会相应地刺激它们的氧化速率。因此,非脂肪营养素摄入与氧化之间的长期失衡不会导致肥胖。另一方面,脂肪储备不受控制,其扩张能力巨大。由于脂肪摄入量的增加不会刺激脂肪氧化,会导致脂肪呈正平衡,这有可能会变成长期状态。因此,肥胖是由于长期的脂肪正平衡,这可能仅仅是由于高脂肪饮食所致。使用脂肪平衡方程而非能量平衡方程为肥胖治疗增加了另一种选择——即改变饮食质量,也就是降低脂肪含量。