Dion I, Rouais F, Trut L, Baquey C, Monties J R, Havlik P
INSERM U.306, Université de Bordeaux II, France.
Biomaterials. 1993 Feb;14(3):169-76. doi: 10.1016/0142-9612(93)90019-x.
The left ventricular assist device under consideration is based on the principle of the Maillard-Wankel rotary pump. The construction materials must meet stringent requirements. Titanium nitride was chosen for its surface properties and graphite for its bulk characteristics. The purpose of this study was to characterize the chemical vapour deposition titanium nitride coating via morphology, roughness, crystallinity, chemical composition, to report and discuss the results of in vitro haemocompatibility tests (protein adsorption, platelet retention, haemolysis) and to discuss physico-chemical and biological results. This chemical vapour deposition titanium nitride coating is well tolerated by the blood despite its surface irregularities, and appears as a good candidate material after improvements.
正在考虑的左心室辅助装置基于迈拉德-汪克尔旋转泵的原理。其建筑材料必须满足严格的要求。选择氮化钛是因其表面特性，选择石墨是因其整体特性。本研究的目的是通过形态、粗糙度、结晶度、化学成分来表征化学气相沉积氮化钛涂层，报告并讨论体外血液相容性测试（蛋白质吸附、血小板滞留、溶血）的结果，并讨论物理化学和生物学结果。尽管这种化学气相沉积氮化钛涂层表面不平整，但血液对其耐受性良好，改进后似乎是一种很好的候选材料。
