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[来自纳瓦拉的一项研究。高脂血症。儿童和青少年群体中血脂和脂蛋白的平均得分及百分位数。与人体测量参数的相关性]

[A study from Navarra. Hyperlipidemias. Avarage scores and percentiles for lipids and lipoproteins in a population of children and adolescents. Correlation with anthropometric parameters].

作者信息

Elcarte López R, Villa-Elizaga I, Sada Goñi J, Gasco Eguiluz M, Oyarzábal Irigoyen M, Sola Mateos A, García Ibero C, Elcarte López T, Ferrer Giménez M, Fontaneda Estíbaliz A

机构信息

Unidad de Endocrinología Pediátrica, Hospital Virgen del Camino, Pamplona, Navarra.

出版信息

An Esp Pediatr. 1993 Apr;38(4):307-15.

PMID:8480942
Abstract

As part of an epidemiological study on cardiovascular risk factors among children and adolescents in Navarra, the following parameters: total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides and C/HDL and LDL/HDL risk quotients were determined in 5,829 children. These children, of both sexes and between the ages of 4 and 17 years, were selected at random from the school population in our community. Average values and percentiles of these parameters were obtained for each group according to age and sex as a previous step to define the health condition or "lipid risk" in our population. When determining the correlation of these biochemical parameters with the anthropometrical parameters of BP, age, weight, height, Quetelet Index, body mass surface, skinfold thickness and the percentage of subcutaneous fat (after the necessary logarithmic transformations, adjusted to each age and sex group by Z-scores) we find that none of the correlation coefficients are significant. The triglycerides and the HDL-cholesterol have a low, but significant. The triglycerides and the HDL-cholesterol have a low, but significantly, correlation with the other lipid parameters. The lipid risk quotient (C/HDL, LDL/HDL) shows a higher correlation with LDL-cholesterol than with total cholesterol.

摘要

作为纳瓦拉地区儿童和青少年心血管危险因素流行病学研究的一部分,对5829名儿童测定了以下参数:总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯以及C/HDL和LDL/HDL风险商数。这些年龄在4至17岁之间的儿童,无论男女,均从我们社区的学校人群中随机选取。作为定义我们人群健康状况或“血脂风险”的前期步骤,根据年龄和性别获得了每组这些参数的平均值和百分位数。在确定这些生化参数与血压、年龄、体重、身高、克托莱指数、体表面积、皮褶厚度和皮下脂肪百分比等人体测量参数的相关性时(经过必要的对数转换后,通过Z分数对每个年龄和性别组进行调整),我们发现没有一个相关系数具有显著性。甘油三酯和高密度脂蛋白胆固醇具有较低但显著的相关性。甘油三酯与其他血脂参数以及高密度脂蛋白胆固醇与其他血脂参数之间具有较低但显著的相关性。血脂风险商数(C/HDL、LDL/HDL)与低密度脂蛋白胆固醇的相关性高于与总胆固醇的相关性。

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