[可溶性免疫复合物诱导趋化作用]
[Induction of chemotaxis by soluble immune complexes].
作者信息
Tack J L, Maillard J, Voisin G A
出版信息
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):255-7.
PMID:848882
Abstract
These complexes, obtained either by adding antigen in excess to immune sera or by redissolving an immune precipitate with antigen, could in the presence of fresh serum stimulate PMN leucocytes to migrate. Complexes with a molecular composition Ab1Ag1 (ot C fixing) showed higher activity than complexes of larger size. The experiments suggest that they activate some sequence of the contact system of coagulation.
摘要
这些复合物，可通过向免疫血清中过量添加抗原或用抗原重新溶解免疫沉淀物来获得，在新鲜血清存在的情况下能够刺激中性粒细胞迁移。分子组成为Ab1Ag1（或C固定）的复合物比更大尺寸的复合物表现出更高的活性。实验表明它们激活了凝血接触系统的某些环节。
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