采用Bactec放射测量系统对酵母进行两性霉素B药敏试验。
Amphotericin B susceptibility testing of yeasts with a bactec radiometric system.
作者信息
Hopfer R L, Gröschel D
出版信息
Antimicrob Agents Chemother. 1977 Feb;11(2):277-80. doi: 10.1128/AAC.11.2.277.
The effect of amphotericin B on CO(2) production was studied using a Bactec 225. A radiometric procedure for yeast susceptibility testing that requires 3 h of incubation was developed. A total of 48 yeast isolates was tested in this system and the results were correlated to tube dilution studies. The drug concentration causing at least a 44% decrease in CO(2) production correlated to the tube dilution minimal inhibitory concentration in 85% of isolates tested and was within one tube dilution of the minimal inhibitory concentration in over 95% of yeasts tested.
使用Bactec 225研究两性霉素B对二氧化碳产生的影响。开发了一种用于酵母药敏试验的放射性测定方法，该方法需要3小时的培养。在该系统中总共测试了48株酵母分离株，并将结果与试管稀释研究进行了关联。导致二氧化碳产生至少减少44%的药物浓度与85%的测试分离株的试管稀释最低抑菌浓度相关，并且在超过95%的测试酵母的最低抑菌浓度的一个试管稀释范围内。
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