细菌素肠膜菌素Y105对单核细胞增生李斯特菌和线粒体的膜通透化作用
Membrane permeabilization of Listeria monocytogenes and mitochondria by the bacteriocin mesentericin Y105.
作者信息
Maftah A, Renault D, Vignoles C, Héchard Y, Bressollier P, Ratinaud M H, Cenatiempo Y, Julien R
机构信息
Institut de Biotechnologie, Faculté des Sciences, Limoges, France.
出版信息
J Bacteriol. 1993 May;175(10):3232-5. doi: 10.1128/jb.175.10.3232-3235.1993.
Abstract
Mesentericin Y105, a bacteriocin produced by a Leuconostoc mesenteroides strain, dissipates the plasma membrane potential of Listeria monocytogenes and inhibits the transport of leucine and glutamic acid. It also induces an efflux of preaccumulated amino acids from cells. In addition, the bacteriocin uncouples mitochondria by increasing state 4 respiration and decreasing state 3 respiration. The bacteriocin inhibits ATP synthase and adenine nucleotide translocase of the organelle while the affinity of ADP for its carrier is not modified. The results suggest that mesentericin Y105 acts by inducing, directly or indirectly, pore formation in the energy-transducing membranes, especially those of its natural target.
摘要
肠膜明串珠菌素Y105是由肠系膜明串珠菌菌株产生的一种细菌素，它可消除单核细胞增生李斯特菌的质膜电位，并抑制亮氨酸和谷氨酸的转运。它还能诱导细胞内预先积累的氨基酸外流。此外，该细菌素通过增加4态呼吸并降低3态呼吸来解偶联线粒体。该细菌素抑制该细胞器的ATP合酶和腺嘌呤核苷酸转位酶，而ADP对其载体的亲和力未发生改变。结果表明，肠膜明串珠菌素Y105的作用机制是直接或间接诱导能量转换膜，尤其是其天然靶标的能量转换膜形成孔道。
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本文引用的文献
1
A MODIFIED TECHNIC OF CUTTING THE EGG SHELL FOR VIRUS CULTURE.
Science. 1944 Aug 18;100(2590):155-6. doi: 10.1126/science.100.2590.155.
2
Colicins and other bacteriocins with established modes of action.具有既定作用方式的大肠杆菌素及其他细菌素。
Annu Rev Microbiol. 1982;36:125-44. doi: 10.1146/annurev.mi.36.100182.001013.
3
Studies on the mechanism of action of channel-forming colicins using artificial membranes.利用人工膜对形成通道的大肠杆菌素作用机制的研究。
J Membr Biol. 1984;79(2):105-18. doi: 10.1007/BF01872115.
4
Localization of the immunity protein-reactive domain in unmodified and chemically modified COOH-terminal peptides of colicin E1.免疫蛋白反应结构域在未修饰和化学修饰的大肠杆菌素E1羧基末端肽段中的定位
J Bacteriol. 1985 Oct;164(1):237-44. doi: 10.1128/jb.164.1.237-244.1985.
5
Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles.肽抗生素乳链菌肽的作用模式及其对全细胞膜电位以及细胞质膜和人工膜囊泡的影响。
Antimicrob Agents Chemother. 1985 May;27(5):841-5. doi: 10.1128/AAC.27.5.841.
6
Bioenergetic consequences of lactose starvation for continuously cultured Streptococcus cremoris.连续培养的嗜热链球菌乳糖饥饿的生物能量学后果
J Bacteriol. 1987 Apr;169(4):1460-8. doi: 10.1128/jb.169.4.1460-1468.1987.
7
Mode of action of the staphylococcinlike peptide Pep 5: voltage-dependent depolarization of bacterial and artificial membranes.类葡萄球菌素样肽Pep 5的作用模式：细菌膜和人工膜的电压依赖性去极化
J Bacteriol. 1988 Jan;170(1):84-8. doi: 10.1128/jb.170.1.84-88.1988.
8
Bioenergetics and solute transport in lactococci.乳酸乳球菌中的生物能量学与溶质转运
Crit Rev Microbiol. 1989;16(6):419-76. doi: 10.3109/10408418909104474.
9
The peptide antibiotic subtilin acts by formation of voltage-dependent multi-state pores in bacterial and artificial membranes.肽抗生素枯草菌素通过在细菌膜和人工膜中形成电压依赖性多态孔来发挥作用。
Eur J Biochem. 1989 Jun 1;182(1):181-6. doi: 10.1111/j.1432-1033.1989.tb14815.x.
10
Mechanism of action of lactostrepcin 5, a bacteriocin produced by Streptococcus cremoris 202.乳酸乳球菌素5的作用机制，乳酸乳球菌素5是由乳脂链球菌202产生的一种细菌素。
Appl Environ Microbiol. 1985 Apr;49(4):969-74. doi: 10.1128/aem.49.4.969-974.1985.
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