Dyduch A, Karczewska K, Grzybek H, Kamiński M
Silesian Paediatric Center, Silesian School of Medicine, Zabrze, Poland.
J Pediatr Gastroenterol Nutr. 1993 Apr;16(3):269-72. doi: 10.1097/00005176-199304000-00008.
The structure of microvilli of intestinal epithelial cells was investigated in 70 children: 34 with celiac disease in remission, 28 with transient gluten enteropathy after a gluten-free diet, and eight controls. Transmission electron microscopy was used to determine the mean thickness of the glycocalyx layer covering the microvilli, the mean length and width of microvilli, and the number of microvilli per 1 micron length of enterocyte surface. The structure of the glycocalyx was found to be intact, but in some children with treated celiac disease the layer of glycocalyx was either thin or absent on the surface of individual cell microvilli. In children with treated celiac disease, microvilli were statistically significantly shorter than those in children with transient gluten enteropathy and controls. Microvillous width in treated celiac disease was greater as compared with that in controls. There was no difference in the number of microvilli on the enterocyte surface in the three groups.
对70名儿童的肠上皮细胞微绒毛结构进行了研究：34名乳糜泻缓解期患儿、28名无麸质饮食后出现短暂性麸质肠病的患儿以及8名对照儿童。采用透射电子显微镜测定覆盖微绒毛的糖萼层的平均厚度、微绒毛的平均长度和宽度以及每1微米肠上皮细胞表面微绒毛的数量。发现糖萼结构完整，但在一些接受治疗的乳糜泻患儿中，个别细胞微绒毛表面的糖萼层较薄或缺失。在接受治疗的乳糜泻患儿中，微绒毛在统计学上显著短于短暂性麸质肠病患儿和对照儿童。与对照相比，接受治疗的乳糜泻患儿的微绒毛宽度更大。三组肠上皮细胞表面微绒毛的数量没有差异。
