大鼠膈肌在体外释放丙氨酸的情况。
The release of alanine by rat diaphragm muscle in vitro.
作者信息
Snell K, Duff D A
出版信息
Biochem J. 1977 Feb 15;162(2):399-403. doi: 10.1042/bj1620399.
Abstract
Alanine release by rat diaphragm muscle in vitro is stimulated by glutamate, valine, leucine and glucose. The stimulation by glutamate and valine (but not leucine) is inhibited by 3-mercaptopicolinate. These results suggest a metabolic route involving phosphoenolpyruvate carboxykinase which directs amino acid carbon skeletons towards pyruvate synthesis for alanine formation.
摘要
体外培养的大鼠膈肌释放丙氨酸受到谷氨酸、缬氨酸、亮氨酸和葡萄糖的刺激。谷氨酸和缬氨酸（而非亮氨酸）的刺激作用受到3-巯基吡啶甲酸盐的抑制。这些结果提示了一条涉及磷酸烯醇式丙酮酸羧激酶的代谢途径，该途径将氨基酸碳骨架导向丙酮酸合成以形成丙氨酸。
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本文引用的文献
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