Scott D W, Miller W H
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853.
J S Afr Vet Assoc. 1993 Mar;64(1):52-6.
Pruritus associated with allergic skin diseases is an important reason for consultation in canine medicine. The pathophysiology of pruritus is poorly understood in the dog, but histamine, leukotrienes, and prostaglandins appear to be important mediators. The medical management of allergic pruritus in dogs with nonsteroidal anti-inflammatory agents is discussed. Antihistamines, tricyclic antidepressants, and omega-3/omega-6 fatty acid-containing products are often useful, either as single agents, in combinations, or for reducing glucocorticoid requirements.
与过敏性皮肤病相关的瘙痒是犬类医学中重要的问诊原因。犬类瘙痒的病理生理学尚不清楚，但组胺、白三烯和前列腺素似乎是重要的介质。本文讨论了使用非甾体抗炎药对犬类过敏性瘙痒进行药物治疗的方法。抗组胺药、三环类抗抑郁药以及含ω-3/ω-6脂肪酸的产品通常很有用，可单独使用、联合使用或用于减少糖皮质激素的用量。
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