Polasa K, Babu S, Shenolikar I S
National Institute of Nutrition, Jamai-Osmania, Hyderabad, India.
Food Chem Toxicol. 1993 Jun;31(6):439-42. doi: 10.1016/0278-6915(93)90160-z.
Aqueous extracts of different brands of pan masala and scented supari were tested for mutagenicity by the Salmonella typhimurium assay using tester strains TA98 and TA100. These extracts were found to be mutagenic to both tester strains. The mutagenic effects of pan masala and scented supari extracts were similar to that produced by areca nut extract. The addition of 500 ppm saccharin to the supari extracts did not alter the mutagenic response.
使用鼠伤寒沙门氏菌TA98和TA100测试菌株，通过鼠伤寒沙门氏菌试验对不同品牌的印度嚼烟和调味槟榔进行水提取物的致突变性测试。发现这些提取物对两种测试菌株均具有致突变性。印度嚼烟和调味槟榔提取物的致突变作用与槟榔提取物产生的作用相似。在槟榔提取物中添加500 ppm糖精不会改变致突变反应。
