Steven F S, Payne P W, Palcic B
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester, U.K.
Anticancer Res. 1993 Mar-Apr;13(2):311-5.
Mature epithelial cells derived from the sputum of normal healthy adults lack GB, while the epithelial cells of sputum collected from patients with lung tumours contain a spectrum of epithelial cells with active GB, some of which are clearly tumour cells, based upon their morphology. The presence of abnormal epithelial cells was confirmed by the cytologist whilst observing the fluorescent stained cells and later by independent cytological analysis of these same cells employing conventional stains.
源自正常健康成年人痰液的成熟上皮细胞缺乏GB,而从肺癌患者收集的痰液中的上皮细胞含有一系列具有活跃GB的上皮细胞,根据其形态,其中一些显然是肿瘤细胞。细胞学家在观察荧光染色细胞时证实了异常上皮细胞的存在,随后通过使用传统染色对这些相同细胞进行独立的细胞学分析再次证实。