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从肺癌患者肺部获取的细胞涂片异常细胞的荧光定位。

Fluorescent location of abnormal cells in cell smears obtained from the lungs of patients with lung cancer.

作者信息

Steven F S, Lam S, Macaulay C, Palcic B

机构信息

Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester, UK.

出版信息

Anticancer Res. 1992 May-Jun;12(3):625-9.

PMID:1622117
Abstract

A bronchoscope fitted with a brush was used to collect cells from patients with lung tumours. The cells were either made into smears or deposited as monolayers on microscope slides. Using a fluorescent probe for the cell surface enzyme, referred to as guanidinobenzoatase, abnormal cells were readily distinguished from normal cells which lacked this enzyme.

摘要

使用装有刷子的支气管镜从肺癌患者身上采集细胞。这些细胞要么制成涂片,要么以单层形式沉积在显微镜载玻片上。使用一种针对细胞表面酶(称为胍基苯甲酸酶)的荧光探针,异常细胞很容易与缺乏这种酶的正常细胞区分开来。

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