Steven F S, Lam S, Macaulay C, Palcic B
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester, UK.
Anticancer Res. 1992 May-Jun;12(3):625-9.
A bronchoscope fitted with a brush was used to collect cells from patients with lung tumours. The cells were either made into smears or deposited as monolayers on microscope slides. Using a fluorescent probe for the cell surface enzyme, referred to as guanidinobenzoatase, abnormal cells were readily distinguished from normal cells which lacked this enzyme.
使用装有刷子的支气管镜从肺癌患者身上采集细胞。这些细胞要么制成涂片,要么以单层形式沉积在显微镜载玻片上。使用一种针对细胞表面酶(称为胍基苯甲酸酶)的荧光探针,异常细胞很容易与缺乏这种酶的正常细胞区分开来。