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Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro.

作者信息

Piedimonte G, Montroni M, Silvestri G, Silvotti L, Donatini A, Rossi L, Borghetti A F, Magnani M

机构信息

Institute of General Pathology, University of Parma, Italy.

出版信息

Arch Virol. 1993;130(3-4):463-9. doi: 10.1007/BF01309674.

Abstract

The addition of ingestable particles (opsonized erythrocytes or latex beads) or a phorbol ester activates monocytes--derived human macrophages (MDHM) cultured in vitro, and markedly reduces virion release from HIV-infected MDHM as well as their ability to transmit the infection to cocultured lymphoid CD4-positive CEM cells.

摘要

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