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Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro.

作者信息

Piedimonte G, Montroni M, Silvestri G, Silvotti L, Donatini A, Rossi L, Borghetti A F, Magnani M

机构信息

Institute of General Pathology, University of Parma, Italy.

出版信息

Arch Virol. 1993;130(3-4):463-9. doi: 10.1007/BF01309674.

DOI:10.1007/BF01309674
PMID:8517797
Abstract

The addition of ingestable particles (opsonized erythrocytes or latex beads) or a phorbol ester activates monocytes--derived human macrophages (MDHM) cultured in vitro, and markedly reduces virion release from HIV-infected MDHM as well as their ability to transmit the infection to cocultured lymphoid CD4-positive CEM cells.

摘要

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本文引用的文献

1
Slow virus replication: the role of macrophages in the persistence and expression of visna viruses of sheep and goats.慢病毒复制：巨噬细胞在绵羊和山羊维斯纳病毒持续存在及表达中的作用
J Gen Virol. 1982 Apr;59(Pt 2):345-56. doi: 10.1099/0022-1317-59-2-345.
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Cytokines alter production of HIV-1 from primary mononuclear phagocytes.细胞因子会改变原代单核吞噬细胞中HIV-1的产生。
Science. 1988 Sep 23;241(4873):1673-5. doi: 10.1126/science.241.4873.1673.
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Microassays for superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using an enzyme immunoassay microplate reader.
使用酶免疫分析微孔板读数仪对超氧化物和过氧化氢生成以及硝基蓝四氮唑还原进行微量分析。
Methods Enzymol. 1986;132:407-21. doi: 10.1016/s0076-6879(86)32026-3.
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Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B.
Nature. 1989 May 4;339(6219):70-3. doi: 10.1038/339070a0.
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Biology and pathogenesis of lentiviruses.慢病毒的生物学与发病机制。
J Gen Virol. 1989 Jul;70 ( Pt 7):1617-39. doi: 10.1099/0022-1317-70-7-1617.
6
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.肿瘤坏死因子α和白细胞介素1通过激活核因子κB来刺激人类免疫缺陷病毒增强子。
Proc Natl Acad Sci U S A. 1989 Apr;86(7):2336-40. doi: 10.1073/pnas.86.7.2336.
7
Infection of peritoneal macrophages in vitro and in vivo with feline immunodeficiency virus.猫免疫缺陷病毒在体外和体内对腹膜巨噬细胞的感染
J Virol. 1989 Dec;63(12):5483-8. doi: 10.1128/JVI.63.12.5483-5488.1989.
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In vitro modification of human immunodeficiency virus infection by granulocyte-macrophage colony-stimulating factor and gamma interferon.粒细胞巨噬细胞集落刺激因子和γ干扰素对人免疫缺陷病毒感染的体外修饰作用
Proc Natl Acad Sci U S A. 1986 Nov;83(22):8734-8. doi: 10.1073/pnas.83.22.8734.
9
HIV-1 infection of normal human macrophage cultures: implication for silent infection.正常人巨噬细胞培养物的HIV-1感染：对潜伏感染的意义。
Virology. 1990 Aug;177(2):790-4. doi: 10.1016/0042-6822(90)90551-2.
10
Systematic classification of HIV biological subtypes on lymphocytes and monocytes/macrophages.基于淋巴细胞和单核细胞/巨噬细胞对HIV生物亚型进行系统分类。
Virology. 1990 Oct;178(2):597-602. doi: 10.1016/0042-6822(90)90361-t.