Vindel A, Trincado P, Martín de Nicolás M M, Gómez E, Martín Bourgon C, Sáez Nieto J A
Laboratorio de Referencia de fagotipia de Staphylococcus aureus, Instituto de Salud Carlos III, Madrid, Spain.
Epidemiol Infect. 1993 Jun;110(3):533-41. doi: 10.1017/s0950268800050950.
This study was undertaken to determine the distribution of phage types of Staphylococcus aureus isolates from hospital outbreaks or sporadic cases received in our laboratory during the past 14 years. The records for 15,803 isolates from 55 Spanish hospitals have been analysed. In relation to sporadic isolates we have been able to detect the predominance of phage group I and non-typable staphylococcal strains. Since 1989, we have observed a considerable increase in hospital infection caused by methicillin-resistant S. aureus strains which we could differentiate in to two groups; one belonging to phage group III (6/47/54/75/77/84/85) and other groups of nontypable strains which could be classified as phage group I-III after heat treatment (29/77/84) and with similar patterns by reverse typing (6/47/53/54/75/83A/84/85/W57/1030/18042). During 1990 and 1991, these strains have extended widely to at least six different autonomous regions creating an epidemic situation in Spain.
本研究旨在确定过去14年中从我院实验室接收的医院暴发或散发病例中分离出的金黄色葡萄球菌噬菌体类型的分布情况。分析了来自55家西班牙医院的15803株分离菌的记录。关于散发分离株，我们已检测到噬菌体I群和不可分型葡萄球菌菌株占优势。自1989年以来，我们观察到耐甲氧西林金黄色葡萄球菌菌株引起的医院感染显著增加，这些菌株可分为两组；一组属于噬菌体III群（6/47/54/75/77/84/85），另一组为不可分型菌株，经热处理（29/77/84）后可归类为噬菌体I-III群，反向分型具有相似模式（6/47/53/54/75/83A/84/85/W57/1030/18042）。在1990年和1991年期间，这些菌株广泛传播至至少六个不同的自治区，在西班牙造成了疫情。
