Espejo Romero H, Navarrete Siancas J
Dpto. de Enfermedades, Ap. Digestivo del Hospital E. Rebagliati, IPSS Lima.
Rev Gastroenterol Peru. 1995;15 Suppl 1:S46-70.
It is difficult to precise when the diverse phenomenons that precede Gastric Cancer start. Diverse events occur in between from the genetic alternations to the advanced gastric carcinoma: inflammatory changes like gastritis, erosions, ulcerations, hyperplasia and benign neoplasias as the adenomas. On these lesions, dysplasia and later on early gastric carcinoma are established. These events have been observed and interpreted, some times in an outstanding way, by diverse authors. The current concept of the link between dysplasia and early gastric cancer is irrefutable.
很难精确确定胃癌之前出现的各种现象是何时开始的。从基因改变到进展期胃癌之间会发生各种各样的情况:诸如胃炎、糜烂、溃疡、增生以及像腺瘤这样的良性肿瘤等炎症变化。在这些病变基础上,会出现发育异常,进而发展为早期胃癌。不同的作者对这些情况进行了观察和解读,有些时候解读得非常出色。发育异常与早期胃癌之间联系的当前概念是无可辩驳的。