Tchaou W S, Turng B F, Minah G E, Coll J A
University of Maryland Dental School at Baltimore, USA.
Pediatr Dent. 1995 Sep-Oct;17(5):351-5.
The primary tooth pulpectomy is a common clinical procedure. The choice of filling material is important to the success rate, but antibacterial properties of such materials against organisms known to inhabit infected primary root canals have not been well documented. This study compared the antibacterial effectiveness of 10 materials: 1. Calcium hydroxide mixed with camphorated parachlorophenol (Ca(OH)2+CPC) 2. Calcium hydroxide mixed with sterile water (Ca(OH)2+H2O) 3. Zinc oxide mixed with CPC (ZnO+CPC) 4. Zinc oxide mixed with eugenol (ZOE) 5. ZOE mixed with formocresol (ZOE+FC) 6. Zinc oxide mixed with sterile water (ZnO+H2O) 7. ZOE mixed with chlorhexidine dihydrochloride (ZOE+CHX) 8. Kri paste 9. Vitapex paste 10. Vaseline (control) These materials were compared against microbial specimens obtained from 13 infected primary teeth by using an agar diffusion assay. The results suggest that the materials could be divided into three categories. Category I, with the strongest antibacterial effect included ZnO+CPC, Ca(OH)2+CPC, and ZOE+FC. Category II, with a medium antibacterial effect included ZOE+CHX, Kri, ZOE, and ZnO+H2O. Category III, with no or minimal antibacterial effect included Vitapex, Ca(OH)2+H2O, and Vaseline. There were no significant differences within each category, but there were significant differences between the categories. The one exception was the antibacterial effect of ZOE+FC which was not significantly different from ZOE+CHX, Kri, or ZOE.
乳牙牙髓摘除术是一种常见的临床操作。填充材料的选择对成功率很重要，但此类材料对已知存在于感染乳牙根管中的微生物的抗菌性能尚未得到充分记录。本研究比较了10种材料的抗菌效果：1. 氢氧化钙与樟脑对氯苯酚混合（Ca(OH)₂+CPC）；2. 氢氧化钙与无菌水混合（Ca(OH)₂+H₂O）；3. 氧化锌与CPC混合（ZnO+CPC）；4. 氧化锌与丁香酚混合（ZOE）；5. ZOE与甲醛甲酚混合（ZOE+FC）；6. 氧化锌与无菌水混合（ZnO+H₂O）；7. ZOE与盐酸氯己定混合（ZOE+CHX）；8. Kri糊剂；9. Vitapex糊剂；10. 凡士林（对照）。通过琼脂扩散试验，将这些材料与从13颗感染乳牙中获取的微生物标本进行比较。结果表明，这些材料可分为三类。第一类，抗菌效果最强，包括ZnO+CPC、Ca(OH)₂+CPC和ZOE+FC。第二类，抗菌效果中等，包括ZOE+CHX、Kri、ZOE和ZnO+H₂O。第三类，无抗菌效果或抗菌效果极小，包括Vitapex、Ca(OH)₂+H₂O和凡士林。每类材料内部无显著差异，但不同类别之间存在显著差异。唯一的例外是ZOE+FC的抗菌效果与ZOE+CHX、Kri或ZOE无显著差异。
