Buch J P, Zorn B H
Surgical Research Center, University of Connecticut Health Center, Farmington 06030-3955.
J Urol. 1993 May;149(5 Pt 2):1350-4. doi: 10.1016/s0022-5347(17)36389-9.
A total of 18 men older than 19 years with spinal cord injury was evaluated for fertility potential with testing of semen obtained by rectal probe electroejaculation. After fertility testing, including sperm penetration assay, semen cryopreservation and sperm antibody status, 6 of the 18 men proceeded with their partners to use rectal probe electroejaculation in efforts to conceive. Sperm was obtained in 16 of 18 cases. Average ejaculate total sperm count (306 million) was good but motility (22%) was poor. Adequate sperm retrieval after processing yielded a normal sperm penetration assay in 4 of 16 cases (25%) in which sperm were obtained. Favorable semen cryopreservation (greater than 33% of pre-freeze motility noted after thaw) was present in 5 of 16 cases (31%). Live births were achieved in 2 of 6 couples attempting conception. Despite the typically poor sperm motility noted in electroejaculates, rectal probe electroejaculation can result in pregnancies from couples involving spinal cord injured men. The sperm penetration assay data indicate that pregnancy should be achievable in at least 25% of spinal cord injured couples. Achieving these conceptions requires a team approach involving a urologist/andrologist, gynecologist/reproductive endocrinologist and a sperm-processing laboratory.
对18名年龄超过19岁的脊髓损伤男性进行了生育潜力评估，通过直肠探头电射精获取精液进行检测。在进行包括精子穿透试验、精液冷冻保存和精子抗体状态检测等生育力检测后，18名男性中有6人与伴侣一起尝试通过直肠探头电射精受孕。18例中有16例成功获取了精子。平均射精总精子数（3亿600万）良好，但活力（22%）较差。在获取精子的16例中，有4例（25%）经过处理后获得足够的精子，精子穿透试验结果正常。16例中有5例（31%）精液冷冻保存效果良好（解冻后活力大于冷冻前的33%）。6对尝试受孕的夫妇中有2例成功分娩。尽管电射精的精子活力通常较差，但直肠探头电射精可使涉及脊髓损伤男性的夫妇受孕。精子穿透试验数据表明，至少25%的脊髓损伤夫妇应该能够受孕。实现这些受孕需要一个团队协作，包括泌尿科医生/男科医生、妇科医生/生殖内分泌学家以及一个精子处理实验室。
