Dewarrat A, Regli F, Steck A, Küntzer T
Service de Neurologie Centre Hospitalier Universitaire Vaudois, Lausanne.
Schweiz Arch Neurol Psychiatr (1985). 1995;146(4):180-4.
In the present report, an unusual case of recurrent Miller Fisher syndrome is described. The patient presented within ten years three similar episodes of ophthalmoplegia, ataxia and areflexia associated with oropharyngeal weakness and signs of mild distal sensory neuropathy. An elevated titer of anti-GQ1b ganglioside antibodies correlated well with the clinical symptoms and signs. The pathogenic role of these antibodies in Miller Fisher syndrome is discussed.
在本报告中,描述了一例复发性米勒-费希尔综合征的罕见病例。该患者在十年内出现了三次类似的眼肌麻痹、共济失调和无反射发作,伴有口咽肌无力和轻度远端感觉神经病变的体征。抗GQ1b神经节苷脂抗体滴度升高与临床症状和体征密切相关。讨论了这些抗体在米勒-费希尔综合征中的致病作用。