Ballin A, Arbel E, Kenet G, Berar M, Kohelet D, Tanay A, Zakut H, Meytes D
Paediatric Haematology Unit, Edith Wolfson Medical Center, Holon, Israel.
Arch Dis Child Fetal Neonatal Ed. 1995 Nov;73(3):F181-3. doi: 10.1136/fn.73.3.f181.
The purpose of this study was to examine some aspects of umbilical cord blood collection for autologous transfusion in premature infants. All 120 microbacterial cultures (aerobic and anaerobic) of cord blood samples as well as 30 cultures of mycoplasma were treated. Cord prothrombin fragment (F 1 + 2) concentrations were quantified at one and 10 minutes after clamping of the cord. F 1 + 2 concentrations assessed on 25 newborn infants were similar and no linear association with time of clamping could be drawn. This means that cord blood thrombosis is not activated for at least 10 minutes following clamping of the cord. As far as is known, the first newborn infant to benefit from this method of transfusion is reported here. The premature infant received two portions of autologous blood (on days 5 and 7). No untoward effects were noted. Blood, collected from the umbilical cord, is a safe source for autotransfusion, provided that bacteriological testing has been carried out.
本研究的目的是探讨早产儿自体输血脐带血采集的某些方面。对所有120份脐带血样本的微生物培养（需氧和厌氧）以及30份支原体培养进行了处理。在脐带夹紧后1分钟和10分钟对脐带凝血酶原片段（F 1 + 2）浓度进行定量。对25名新生儿评估的F 1 + 2浓度相似，且无法得出与夹紧时间的线性关联。这意味着脐带夹紧后至少10分钟内脐带血血栓形成未被激活。据所知，本文报道了首例受益于这种输血方法的新生儿。该早产儿接受了两份自体血（第5天和第7天）。未观察到不良影响。只要进行了细菌学检测，从脐带采集的血液是自体输血的安全来源。
