鼠疫耶尔森菌菌株的体外抗菌药敏情况
In vitro antimicrobial susceptibilities of strains of Yersinia pestis.
作者信息
Smith M D, Vinh D X, Nguyen T T, Wain J, Thung D, White N J
机构信息
Wellcome Trust Clinical Research Unit, Cho Quan Hospital, Ho Chi Minh City, Vietnam.
出版信息
Antimicrob Agents Chemother. 1995 Sep;39(9):2153-4. doi: 10.1128/AAC.39.9.2153.
Abstract
The in vitro activities of 14 antimicrobial agents were determined for 78 strains of Yersinia pestis. The most active antibiotics were ceftriaxone and ciprofloxacin, followed by ofloxacin and ampicillin. The agents traditionally used for the treatment of plague (streptomycin, tetracycline, and chloramphenicol) were considerably less active. Azithromycin showed poor activity against all strains.
摘要
测定了14种抗菌药物对78株鼠疫耶尔森菌的体外活性。活性最强的抗生素是头孢曲松和环丙沙星，其次是氧氟沙星和氨苄西林。传统上用于治疗鼠疫的药物（链霉素、四环素和氯霉素）活性要低得多。阿奇霉素对所有菌株的活性都很差。
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