雌二醇对大鼠子宫中前列腺素代谢的影响。

Effect of estradiol on prostaglandin metabolism in rat uterus.

作者信息

Kogo H, Yamada K, Aizawa Y

出版信息

Prostaglandins. 1977 Apr;13(4):785-94. doi: 10.1016/0090-6980(77)90252-0.

Abstract

The purpose of this work was to investigate the effect of a single injection of estradiol (10 microng/rat) on prostaglandin(PG) metabolism in rat uterus. The PG content of uterus was increased within 6 hr after estradiol injection but the incorporation of 3H-arachidonic acid into PG in uterus was not changed within same period. The uptake of 3H-PG was increased within 6 hr after estradiol injection. In these results, it is discussed that PG from other tissue are also involved in the metabolism of PG in uterus.

摘要

本研究旨在探讨单次注射雌二醇（10微克/大鼠）对大鼠子宫前列腺素（PG）代谢的影响。注射雌二醇后6小时内，子宫内PG含量增加，但同一时期子宫内3H-花生四烯酸掺入PG的量未发生变化。注射雌二醇后6小时内，3H-PG的摄取增加。基于这些结果，讨论了来自其他组织的PG也参与子宫内PG的代谢。