Turner M W, McClelland D B, Medlen A R, Stokes C R
Scand J Immunol. 1977;6(4):343-8. doi: 10.1111/j.1365-3083.1977.tb00403.x.
IgE was found in urine from healthy adult volunteers at very low levels (approximately 0.003-0.010 IU/ml), corresponding to a 24-h excrection rate of 3-16 IU. IgE was not detected in 36 out of 47 samples of milk and colostrum. In samples from six women the protein was present at low concentration 1-2 days postpartum but was not detected in later samples (usually day 5 or 6). Mammary secretions from four allergic donors were studied, and IgE was detected at low concentrations in samples from the two most severely affected individuals. The levels of IgE observed in both urine and milk suggest that there is no significant synthesis of the protein in either the urinary tract or in mammary tissue.
在健康成年志愿者的尿液中发现了极低水平的IgE(约0.003 - 0.010 IU/ml),相当于24小时排泄率为3 - 16 IU。47份牛奶和初乳样本中有36份未检测到IgE。在6名女性的样本中,产后1 - 2天蛋白质浓度较低,但在后期样本(通常是第5天或第6天)中未检测到。对4名过敏供体的乳腺分泌物进行了研究,在两名受影响最严重个体的样本中检测到低浓度的IgE。在尿液和牛奶中观察到的IgE水平表明,尿路或乳腺组织中该蛋白质的合成均不显著。