Cofán M, Fernandez-Solà J, Nicolás J M, Poch E, Urbano-Márquez A
Department of Internal Medicine, Hospital Clínic, University of Barcelona, Spain.
Alcohol Alcohol. 1995 Sep;30(5):617-21.
We analysed the effect of ethanol on basal cytosolic-free calcium concentration ([Ca2+]i) in cultured rat myocytes. Ethanol caused a dose-dependent decrease of the resting [Ca2+]i. Removal of ethanol was followed by a transitory increase of [Ca2+]i above the basal level. In cells chronically exposed to ethanol, [Ca2+]i normalized to the previous level.
我们分析了乙醇对培养的大鼠心肌细胞基础胞质游离钙浓度([Ca2+]i)的影响。乙醇导致静息[Ca2+]i呈剂量依赖性降低。去除乙醇后,[Ca2+]i会短暂升高至基础水平之上。在长期暴露于乙醇的细胞中,[Ca2+]i恢复至先前水平。