Itoh M, Nakano E, Ieshima A, Takeshita K
Division of Child Neurology, Tottori University Faculty of Medicine, Yonago, Japan.
Pediatr Neurol. 1995 Oct;13(3):255-6. doi: 10.1016/0887-8994(95)00155-9.
A 6-year-old boy with striatonigral degeneration had an episode of neuroleptic malignant syndrome after an upper respiratory infection. Dantrolene treatment was successful. Some reports have demonstrated that anesthetic and antipsychotic agents lead to neuroleptic malignant syndrome in disorders of the basal ganglia. However, neuroleptic malignant syndrome attributable to a respiratory infection has not previously been reported. Our patient illustrates the potential morbidity of neuroleptic malignant syndrome in patients with striatonigral degeneration.
一名患有纹状体黑质变性的6岁男孩在上呼吸道感染后发生了一次抗精神病药恶性综合征。丹曲林治疗成功。一些报告表明，麻醉剂和抗精神病药物会在基底神经节疾病中导致抗精神病药恶性综合征。然而，此前尚未有因呼吸道感染导致抗精神病药恶性综合征的报道。我们的患者说明了纹状体黑质变性患者发生抗精神病药恶性综合征的潜在发病率。
