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Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55.肿瘤坏死因子α（TNF-α）诱导的细胞与人内皮细胞的黏附受一种肿瘤坏死因子受体类型TNF-R55的主导控制。
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Soluble tumor necrosis factor receptors in human inflammatory synovial fluids.人类炎性滑液中的可溶性肿瘤坏死因子受体
Arthritis Rheum. 1993 Apr;36(4):485-9. doi: 10.1002/art.1780360408.
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Role of polymorphonuclear neutrophil leukocytes and their integrin CD11a (LFA-1) in the pathogenesis of severe murine malaria.多形核中性粒细胞及其整合素CD11a（淋巴细胞功能相关抗原-1）在重症鼠疟发病机制中的作用
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Immunopathological changes in human cerebral malaria.人类脑型疟疾的免疫病理变化。
Clin Neuropathol. 1993 May-Jun;12(3):142-6.
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Elevated serum levels of circulating intercellular adhesion molecule-1 in HIV infection.
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The role of cell adhesion molecules in immunopathology.
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Increased plasma levels of soluble ICAM-1 and ELAM-1 (E-selectin) during acute Plasmodium falciparum malaria.恶性疟原虫急性感染期间血浆中可溶性细胞间黏附分子-1和E选择素水平升高。
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Circulating adhesion molecules in disease.疾病中的循环黏附分子
Immunol Today. 1993 Oct;14(10):506-12. doi: 10.1016/0167-5699(93)90267-O.
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Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.抗细胞因子单克隆抗体的研发策略：临床样本中白细胞介素-10和白细胞介素-5的免疫测定
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Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1.恶性疟原虫感染红细胞的人血管内皮细胞黏附受体：内皮白细胞黏附分子1和血管细胞黏附分子1的作用
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恶性疟患者血浆中可溶性细胞间黏附分子-1和E-选择素水平及其与肿瘤坏死因子α、白细胞介素1α（IL-1α）和IL-10水平缺乏相关性

Soluble intercellular adhesion molecule-1 and E-selectin levels in plasma of falciparum malaria patients and their lack of correlation with levels of tumor necrosis factor alpha, interleukin 1 alpha (IL-1 alpha), and IL-10.

作者信息

Peyron F, Caux-Menetrier C, Roux-Lombard P, Niyongabo T, Aubry P, Deloron P

机构信息

Parasitology Laboratory, Claude Bernard University, Lyon, France.

出版信息

Clin Diagn Lab Immunol. 1994 Nov;1(6):741-3. doi: 10.1128/cdli.1.6.741-743.1994.

DOI:10.1128/cdli.1.6.741-743.1994
PMID:8556530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC368407/
Abstract

Intercellular adhesion molecule-1 and E-selectin levels were increased in the plasma of 60 falciparum malaria patients and were not related to levels of tumor necrosis factor alpha, interleukin 10, or interleukin 1 alpha. Soluble E-selectin was correlated to disease; its level in plasma was related to levels of both tumor necrosis factor soluble receptors and biological markers of disease severity and returned to baseline after parasite clearance faster than that of soluble intercellular adhesion molecule-1.

摘要

60例恶性疟患者血浆中细胞间黏附分子-1和E-选择素水平升高，且与肿瘤坏死因子α、白细胞介素10或白细胞介素1α水平无关。可溶性E-选择素与疾病相关；其血浆水平与肿瘤坏死因子可溶性受体水平及疾病严重程度的生物学标志物均有关，且在寄生虫清除后恢复至基线水平的速度比可溶性细胞间黏附分子-1更快。