Sahwi S Y, Zaki M S, Haiba N Y, Elsaid O K, Anwar M Y, AbdRabbo S A
Department of Obstetrics and Gynecology, Shatby Maternity University Hospital, Faculty of Medicine, Alexandria University, Egypt.
J Obstet Gynaecol (Tokyo 1995). 1995 Apr;21(2):145-8. doi: 10.1111/j.1447-0756.1995.tb01087.x.
The extent to which toxoplasmosis causes habitual abortion is still controversial. The present study was carried out on 100 cases of repeated abortions, and 40 multiparous pregnant women at 20th week gestation as a control. Tests for the presence of toxoplasma IgG and/or IgM antibodies were done for both groups. It was found that 19% of the selected cases, and 7.5% of the control were seropositive for IgM. The difference was statistically insignificant, therefore acute toxoplasmosis, most probably, is not related to habitual abortions, whereas 37% of the selected cases and only 10% of the control group were seropositive at high dilution for IgG antibody, this statistical significant difference indicates that chronic toxoplasmosis, most probably is a significant cause of repeated abortion. Also it has been found that toxoplasmosis has a significant relation to abortion at first trimester.
弓形虫病导致习惯性流产的程度仍存在争议。本研究对100例反复流产病例进行了调查，并选取40例妊娠20周的经产妇作为对照。对两组均进行了弓形虫IgG和/或IgM抗体检测。结果发现，所选病例中有19%、对照组中有7.5%的IgM血清学呈阳性。差异无统计学意义，因此急性弓形虫病很可能与习惯性流产无关，而所选病例中有37%、对照组中仅有10%的IgG抗体在高稀释度时血清学呈阳性，这一统计学显著差异表明慢性弓形虫病很可能是反复流产的一个重要原因。此外还发现，弓形虫病与孕早期流产有显著关系。
