喀麦隆南部俾格米人及邻近班图人中丙型肝炎病毒和其他血源病毒的流行情况。
Prevalence of hepatitis C virus and other blood-borne viruses in Pygmies and neighbouring Bantus in southern Cameroon.
作者信息
Kowo M P, Goubau P, Ndam E C, Njoya O, Sasaki S, Seghers V, Kesteloot H
机构信息
Department of Gastroenterology and Nutrition, University of Yaoundé, Cameroon.
出版信息
Trans R Soc Trop Med Hyg. 1995 Sep-Oct;89(5):484-6. doi: 10.1016/0035-9203(95)90076-4.
The prevalences of antibodies to hepatitis C virus (anti-HCV), human immunodeficiency virus (anti-HIV), human T lymphotrophic virus (anti-HTLV) and of hepatitis B surface antigen (HbsAg) were determined in 168 subjects aged 12 years and over (108 Pygmies, 60 Bantus) living in south Cameroon. In 167 subjects, we found an estimated minimal anti-HCV prevalence of 13%. The prevalence was significantly higher in Bantus (31.7%) than in Pygmies (11.1%) and increased with age in both groups, albeit more rapidly in Bantus. The overall prevalence of HBsAg was 7.2% and correlated with neither sex nor ethnic group. No association was found between anti-HCV and HbsAg prevalence rates. No subject was confirmed to be positive for HTLV or HIV. These findings confirm the high prevalence of HCV infection in south Cameroon and indicate that even secluded population groups are affected.
在喀麦隆南部生活的168名12岁及以上的受试者（108名俾格米人，60名班图人）中，测定了丙型肝炎病毒抗体（抗-HCV）、人类免疫缺陷病毒抗体（抗-HIV）、人类嗜T淋巴细胞病毒抗体（抗-HTLV）以及乙型肝炎表面抗原（HbsAg）的流行率。在167名受试者中，我们发现抗-HCV估计最低流行率为13%。班图人的流行率（31.7%）显著高于俾格米人（11.1%），且两组的流行率均随年龄增长而上升，不过班图人的上升速度更快。HBsAg的总体流行率为7.2%，与性别和种族均无关联。未发现抗-HCV和HBsAg流行率之间存在关联。未确认有受试者HTLV或HIV呈阳性。这些发现证实了喀麦隆南部HCV感染的高流行率，并表明即使是与世隔绝的人群也受到了影响。
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