喀麦隆东部省俾格米人的感染情况。
Infections among pygmies in the Eastern Province of Cameroon.
作者信息
Ndumbe P M, Atchou G, Biwole M, Lobe V, Ayuk-Takem J
机构信息
Department of Microbiology, Faculty of Medicine and Biomedical Sciences, University of Yaounde, Cameroon.
出版信息
Med Microbiol Immunol. 1993 Dec;182(6):281-4. doi: 10.1007/BF00191943.
The health requirements of pygmies is poorly understood because of their continued isolation from the other tribes in Central Africa. This study was undertaken among the Baka pygmies of the Eastern Province of Cameroon to generate basic health data among them. A total of 141 adults (18-45 years) were tested for the hepatitis B surface antigen (HBsAg), antibody to the surface antigen (anti-HBs), antibody to the core antigen (anti-HBc) and antibody to the hepatitis C virus (anti-HCV). All HBsAg-positive sera were tested for the hepatitis B e antigen (HBeAg) and antibody (anti-HBe). The presence of antibodies to the hepatitis D virus was determined in most of the anti-Hbs-positive sera, and some of the HBsAg-positive sera. In addition to these, previous infection with syphilis, measles, HIV 1/2 and HTLV were determined by looking for the specific antibodies. We found HBsAg in 14.2% (20/141), anti-HBs in 93.6% (132/141), anti-HBs in 52.2% (73/140), anti-HCV in 7.9% (11/139, measles antibody in 99.3% (139/140), antibody to Treponema pallidum in 13.4% (18/134), antibody to HTLV-1 in 10.9% (15/138) and antibody to HIV-1 in 0.7% (1/140) of the sera tested.
由于俾格米人一直与中非的其他部落隔绝，人们对他们的健康需求了解甚少。本研究在喀麦隆东部省的巴卡俾格米人中开展，以获取他们的基本健康数据。共对141名成年人（18至45岁）进行了乙肝表面抗原（HBsAg）、表面抗原抗体（抗-HBs）、核心抗原抗体（抗-HBc）和丙型肝炎病毒抗体（抗-HCV）检测。所有HBsAg阳性血清均检测了乙肝e抗原（HBeAg）和抗体（抗-HBe）。在大多数抗-HBs阳性血清以及部分HBsAg阳性血清中检测了丁型肝炎病毒抗体的存在情况。除此之外，通过查找特异性抗体确定既往梅毒、麻疹、HIV 1/2和HTLV感染情况。我们发现，在所检测的血清中，HBsAg阳性率为14.2%（20/141），抗-HBs阳性率为93.6%（132/141），抗-HBc阳性率为52.2%（73/140），抗-HCV阳性率为7.9%（11/139），麻疹抗体阳性率为99.3%（139/140），梅毒螺旋体抗体阳性率为13.4%（18/134），HTLV-1抗体阳性率为10.9%（15/138），HIV-1抗体阳性率为0.7%（1/140）。
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