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个体暴露于颗粒物空气污染及其与健康影响阈值的相关性:交通协管员研究

Individual exposure to particulate air pollution and its relevance to thresholds for health effects: a study of traffic wardens.

作者信息

Watt M, Godden D, Cherrie J, Seaton A

机构信息

Department of Environmental and Occupational Medicine, University of Aberdeen.

出版信息

Occup Environ Med. 1995 Dec;52(12):790-2. doi: 10.1136/oem.52.12.790.

DOI:10.1136/oem.52.12.790
PMID:8563840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1128378/
Abstract

OBJECTIVE

To investigate the differences between measurements of personal exposure to particulate air pollution and static area measurements in a group of people working close to traffic and to determine whether such differences might obscure any threshold for health effects in epidemiological studies.

METHODS

Personal air sampling was carried out on two groups of eight traffic wardens for four days on two consecutive weeks in November 1994. These measurements were compared with standard environmental static sampling data that were obtained for the same period. A simulation with log normal distributions of personal exposures was produced, and an arbitrary risk calculated for each exposure, assuming a threshold of 50 micrograms/m3, and an exposure-response curve was calculated.

RESULTS

The median concentration for personal samplers in week 1 was 123 micrograms/m3 and 41 micrograms/m3 in week 2. Corresponding area concentrations were 10 micrograms/m3 and 7.5 micrograms/m3. The differences between the personal and area results were significant, as were the differences for personal sampling between weeks 1 and 2. The simulation showed that the variation in individual exposures around an area sampler obscured the threshold.

CONCLUSIONS

Area sampling data may be of limited value in the investigation of the biological effects of exposure to pollution and their use may result in real thresholds being obscured. Personal exposure assessment may be crucial in determination of the health effects attributable to different concentrations of air pollutants.

摘要

目的

调查一组在交通繁忙区域附近工作的人员个人接触颗粒物空气污染的测量值与静态区域测量值之间的差异,并确定这些差异是否可能在流行病学研究中掩盖健康影响的任何阈值。

方法

1994年11月,连续两周对两组共八名交通协管员进行了为期四天的个人空气采样。这些测量值与同期获得的标准环境静态采样数据进行了比较。对个人接触情况进行了对数正态分布模拟,并假设阈值为50微克/立方米,为每次接触计算了一个任意风险值,然后计算了接触-反应曲线。

结果

第1周个人采样器的中位数浓度为123微克/立方米,第2周为41微克/立方米。相应的区域浓度分别为10微克/立方米和7.5微克/立方米。个人测量结果与区域测量结果之间的差异显著,第1周和第2周个人采样结果之间的差异也显著。模拟结果表明,围绕区域采样器的个体接触变化掩盖了阈值。

结论

区域采样数据在调查污染暴露的生物学效应方面可能价值有限,使用这些数据可能会导致实际阈值被掩盖。个人接触评估对于确定不同浓度空气污染物对健康的影响可能至关重要。

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