Moss S, Patel P
Hester Adrian Research Centre, University of Manchester.
Br J Psychiatry. 1995 Nov;167(5):663-7. doi: 10.1192/bjp.167.5.663.
This paper describes a study of non-cognitive features of dementia in a population of 105 people over 50 years of age, with learning disability.
The study involved psychiatric assessment using the Psychiatric Assessment Schedule for Adults with a Developmental Disability (PAS-ADD), a semi-structured psychiatric interview developed specifically for people who have learning disability. Dementia was diagnosed using a combination of informant interviewing and observation of cognitive change over a three year period.
Sample members with definite dementia had higher levels of sleep difficulty, hypersomnia, irritability, inefficient thought, loss of interest and anhedonia. Discriminant function analysis showed that non-cognitive features could help discriminate between definite and probable cases.
Results support the previously reported observation for the general population that cognitive and non-cognitive features are only weakly related. The study suggests that psychiatric symptom information may be useful in screening for dementia in people with learning disability.
本文描述了一项针对105名50岁以上有学习障碍人群的痴呆非认知特征的研究。
该研究采用针对发育障碍成年人的精神病评估量表(PAS - ADD)进行精神病评估,这是一种专门为有学习障碍的人群开发的半结构化精神病访谈。通过信息提供者访谈和对三年期间认知变化的观察相结合来诊断痴呆。
确诊为痴呆的样本成员存在更高水平的睡眠困难、嗜睡、易怒、思维效率低下、兴趣丧失和快感缺失。判别函数分析表明,非认知特征有助于区分确诊病例和疑似病例。
研究结果支持先前针对普通人群的观察结果,即认知特征和非认知特征之间的关联较弱。该研究表明,精神症状信息可能有助于筛查有学习障碍人群中的痴呆。