Dixon P M, Railton D I, McGorum B C
Department of Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, Scotland, UK.
Equine Vet J. 1995 Nov;27(6):428-35. doi: 10.1111/j.2042-3306.1995.tb04423.x.
The majority of 270 adult horses with chronic pulmonary diseases had excessive volumes of respiratory secretions (RS) present in their trachea, elevated tracheal RS neutrophil ratios and lowered arterial oxygen partial pressures. Some control horses, had inexplicably elevated trachael RS neutrophil ratios. Only the chronic obstructive pulmonary disease (COPD) affected group had significantly elevated bronchoalveolar lavage fluid (BALF) neutrophil ratios. Maximal intrapleural pressure changes (max dPpl) were raised in 48% of COPD cases and rarely with other pulmonary disorders. Arterial pH or carbon doxide partial pressures values were seldom altered with any pulmonary diseases. Tracheal RS and BALF eosinophil ratios were raised with lungworm infection and idiopathic pulmonary eosinophilia.
270匹患有慢性肺部疾病的成年马中,大多数马的气管内存在过量的呼吸道分泌物(RS),气管RS中性粒细胞比率升高,动脉血氧分压降低。一些对照马的气管RS中性粒细胞比率莫名升高。只有慢性阻塞性肺疾病(COPD)患病组的支气管肺泡灌洗液(BALF)中性粒细胞比率显著升高。48%的COPD病例最大胸膜内压变化(max dPpl)升高,其他肺部疾病很少出现这种情况。任何肺部疾病很少会改变动脉pH值或二氧化碳分压值。气管RS和BALF嗜酸性粒细胞比率在感染肺线虫和特发性肺嗜酸性粒细胞增多症时升高。