Godel V, Regenbogen L
Ophthalmologica. 1977;174(3):121-8. doi: 10.1159/000308589.
Three patients with central retinitis pigmentosa were investigated in a 5-year follow-up study. The psychophysical and electrophysiological data show the involement of both the central and peripheral photoreceptors and their continuous functional deterioration with time. This conclusion could be demonstrated under all conditions of testing indicating the polymorphism of the disease. The results and the lack of genetical involvement make it difficult to relate this condition to the classical pigmentary retinal degeneration. This data emphasizes the importance of clinical reevaluations and serial electrophysiological testing in order to differentiate between the stationary periods and the progressive deterioration in this disease.
在一项为期5年的随访研究中,对三名中心性视网膜色素变性患者进行了调查。心理物理学和电生理学数据显示,中心和周边光感受器均受累,且其功能随时间持续恶化。在所有测试条件下均可证实这一结论,表明该疾病具有多态性。这些结果以及缺乏遗传因素参与,使得难以将这种情况与经典的视网膜色素变性联系起来。这些数据强调了临床重新评估和系列电生理学测试的重要性,以便区分该疾病的静止期和进行性恶化。