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孕期细菌性阴道病和宫颈炎患者的阴道及宫颈pH值

Vaginal and cervical pH in bacterial vaginosis and cervicitis during pregnancy.

作者信息

Sagawa T, Negishi H, Kishida T, Yamada H, Fujimoto S

机构信息

Department of Obstetrics and Gynecology, Hokkadio University School of Medicine, Sapporo, Japan.

出版信息

Hokkaido Igaku Zasshi. 1995 Nov;70(6):839-46.

PMID:8582707
Abstract

The purpose of our study is to see whether vaginal and cervical pH are helpful to screen for bacterial vaginosis and cervicitis during pregnancy. One hundred and seven pregnant women underwent prospectively both vaginal pH and cervical pH measurement and screening for microbial infections of the lower genital tracts at 10, 20 and 30 gestational week between February 1993 and August 1993. The value of vaginal pH significantly elevated in bacterial vaginosis (P < 0.05). Vaginal pH values also significantly elevated in patients who had had sexual intercourse 2 days before the dates of examinations (P < 0.01). Cervical pH value exhibited no significant change in bacterial vaginosis and cervicitis. Vaginal pH is a valid indicator for screening of bacterial vaginosis during pregnancy. However, vaginal pH might be influenced by the presence of semen. Cervical pH is not a useful parameter for screening of cervicitis during pregnancy.

摘要

我们研究的目的是观察阴道和宫颈pH值是否有助于孕期细菌性阴道病和宫颈炎的筛查。1993年2月至1993年8月期间,107名孕妇在妊娠第10、20和30周时前瞻性地接受了阴道pH值和宫颈pH值测量以及下生殖道微生物感染筛查。细菌性阴道病患者的阴道pH值显著升高(P<0.05)。在检查日期前2天有过性行为的患者中,阴道pH值也显著升高(P<0.01)。宫颈pH值在细菌性阴道病和宫颈炎患者中无显著变化。阴道pH值是孕期筛查细菌性阴道病的有效指标。然而,阴道pH值可能受精液存在的影响。宫颈pH值不是孕期筛查宫颈炎的有用参数。

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引用本文的文献

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Estrogen acidifies vaginal pH by up-regulation of proton secretion via the apical membrane of vaginal-ectocervical epithelial cells.雌激素通过上调阴道-子宫颈外口上皮细胞顶膜的质子分泌来酸化阴道pH值。
Endocrinology. 2005 Feb;146(2):816-24. doi: 10.1210/en.2004-1153. Epub 2004 Oct 21.
2
Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification.阴道菌群在体外产生酸的情况与阴道酸化的速率和程度相符。
Infect Immun. 1999 Oct;67(10):5170-5. doi: 10.1128/IAI.67.10.5170-5175.1999.