Reymond D, Plaschkes J, Lüthy A R, Leibundgut K, Hirt A, Wagner H P
Department of Pediatrics, University Hospitals, Bern, Switzerland.
J Pediatr Surg. 1995 Nov;30(11):1590-3. doi: 10.1016/0022-3468(95)90162-0.
The authors used a conservative approach to treat focal nodular hyperplasia of the liver (FNH) and were interested in the long-term results of different therapeutic approaches in order to establish the most appropriate treatment. A review of the literature was conducted, and 31 pediatric case reports were identified in which follow-up and outcome data were noted. Tumor resection was performed in 18 cases (58%), operative biopsy alone in nine (29%), vascular ligation in two, and embolization of hepatic arteries in two. The outcome appears to be good for both groups of patients, ie, those with observation alone and those with resection. More information is to be collected regarding the new procedures (embolization and ligation). This is a retrospective analysis, and data from future international prospective studies are needed.
作者采用保守方法治疗肝脏局灶性结节性增生（FNH），并对不同治疗方法的长期结果感兴趣，以便确定最合适的治疗方案。他们进行了文献综述，确定了31例儿科病例报告，其中记录了随访和结果数据。18例（58%）进行了肿瘤切除，9例（29%）仅进行了手术活检，2例进行了血管结扎，2例进行了肝动脉栓塞。两组患者（即单纯观察和切除的患者）的结果似乎都很好。关于新的治疗方法（栓塞和结扎）还需要收集更多信息。这是一项回顾性分析，需要未来国际前瞻性研究的数据。
