AL-Nahhas A M, Hjiyiannakis P, Hammersley P A, McCready V R, Horwich A H
Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK.
Eur J Nucl Med. 1995 Dec;22(12):1453-6. doi: 10.1007/BF01791154.
Radiolabelled white cell scanning is widely used to detect the presence of infection. We present a case of non-Hodgkin s lymphoma manifesting with signs and symptoms suggestive of infection, in which a technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) white cell scan demonstrated high uptake in lymph nodes involved by lymphoma. Differential cell analysis showed preferential lymphocyte labelling. The classification and management of the disease were changed accordingly. Our findings suggest that a future role for 99mTc-HMPAO labelled white cells in the assessment of disease activity of lymphoma should be investigated.
放射性标记白细胞扫描被广泛用于检测感染的存在。我们报告一例非霍奇金淋巴瘤病例，其表现出提示感染的症状和体征，其中锝-99m六甲基丙烯胺肟（99mTc-HMPAO）白细胞扫描显示淋巴瘤累及的淋巴结有高摄取。细胞分类分析显示淋巴细胞优先标记。疾病的分类和管理因此发生了改变。我们的研究结果表明，应研究99mTc-HMPAO标记白细胞在评估淋巴瘤疾病活动度方面的未来作用。
