Hararda T, Fukami H, Takeuchi T, Niwa T, Majima Y
Augenklinik Fujita Health University Toyoake.
Klin Monbl Augenheilkd. 1995 Nov;207(5):302-4. doi: 10.1055/s-2008-1035383.
Recently interferons have been utilized for hepatitis C or some other tumorous conditions. However, a new interferon-associated retinopathy has been reported. There are to our knowledge, no publications in German-speaking countries.
Four patients developed after interferon therapy cotton-wool spots combined with splinter hemorrhage.
The retinopathy occurred 5-30 days after the beginning of the therapy. In one case the retinopathy aggravated following dose elevation, whereas in two other cases the cotton-wool spots and hemorrhages disappeared irrespective of continued interferon therapy.
Interferons cannot be primarily responsible for the development of retinopathy.
最近，干扰素已被用于治疗丙型肝炎或其他一些肿瘤疾病。然而，一种新的与干扰素相关的视网膜病变已被报道。据我们所知，在德语国家尚无相关出版物。
4名患者在接受干扰素治疗后出现棉絮斑合并线状出血。
视网膜病变在治疗开始后5 - 30天出现。1例患者在剂量增加后视网膜病变加重，而另外2例患者的棉絮斑和出血在继续使用干扰素治疗的情况下消失。
干扰素并非视网膜病变发生的主要原因。
