Corcoran B M, Foster D J, Fuentes V L
Department of Veterinary Clinical Studies, University of Edinburgh, Summerhall.
J Small Anim Pract. 1995 Nov;36(11):481-8. doi: 10.1111/j.1748-5827.1995.tb02787.x.
Feline asthma syndrome (FAS) is a clinical condition characterised by recurrent bouts of coughing, wheezing and, or, dyspnoea. While the aetiology is unproven, the condition is believed to involve a type I immediate hypersensitivity reaction to inhaled allergens. In this paper the clinical data from 29 cats, where a diagnosis of FAS was made, are assessed retrospectively. The most common clinical presentation was recurrent bouts of coughing (n = 26) and dyspnoea (n = 21). Radiographic changes were noted in 24 cats, which included increased bronchial (n = 5), interstitial (n = 7) and mixed (n = 12) (bronchial and interstitial) patterns. Right middle lung lobe collapse was noted in two cats. Abnormal bronchial cytology was present in 16 cats. A predominant eosinophilic sample was collected in only three cats. There were minimal changes in differential white cell counts, and mild eosinophilia was found in only five cats. Prednisolone alone was the most effective therapy, although avoidance of putative aeroallergens and antibacterial therapy was effective in some. On the basis of the data from these cases it would appear that the diagnosis of FAS depends largely on the clinical presentation and radiographic findings. The value of ancillary tests in the diagnosis of FAS appears to be limited.
猫哮喘综合征（FAS）是一种临床病症，其特征为反复出现咳嗽、喘息和/或呼吸困难。虽然病因尚未得到证实，但据信该病症涉及对吸入性过敏原的I型速发型超敏反应。本文对29只被诊断为FAS的猫的临床数据进行了回顾性评估。最常见的临床表现是反复咳嗽（n = 26）和呼吸困难（n = 21）。24只猫出现了影像学改变，包括支气管（n = 5）、间质（n = 7）和混合（n = 12）（支气管和间质）模式增加。两只猫出现了右中叶肺不张。16只猫的支气管细胞学异常。仅三只猫采集到以嗜酸性粒细胞为主的样本。白细胞分类计数变化极小，仅五只猫发现轻度嗜酸性粒细胞增多。单独使用泼尼松龙是最有效的治疗方法，尽管避免接触假定的空气过敏原和抗菌治疗在某些情况下也有效。根据这些病例的数据，FAS的诊断似乎很大程度上取决于临床表现和影像学检查结果。辅助检查在FAS诊断中的价值似乎有限。
