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患有支气管疾病的猫的临床、放射学和支气管细胞学特征:65例病例(1980 - 1986年)

Clinical, radiographic, and bronchial cytologic features of cats with bronchial disease: 65 cases (1980-1986).

作者信息

Moise N S, Wiedenkeller D, Yeager A E, Blue J T, Scarlett J

机构信息

Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.

出版信息

J Am Vet Med Assoc. 1989 May 15;194(10):1467-73.

PMID:2470710
Abstract

Medical records, radiographs, and bronchial cytologic abnormalities of 65 cats with bronchial disease were reviewed. Bronchial disease was defined as abnormality of the lower airways to the exclusion of disease originating or mainly involving the alveoli, interstitium, vasculature, or pleura. Cats with bronchial disease were more likely to be female and older. Siamese cats were overrepresented and had more chronic disease. In order of frequency, the following clinical signs were reported: coughing, dyspnea, occasional sneezing, wheezing, and vomiting. Radiography revealed prominent bronchial markings, with some cats having collapse of the middle lobe of the right lung (n = 7), overinflation of the lungs (n = 9), or aerophagia (n = 13). Of 65 bronchial washes, 58 were considered exudative, with the predominant cell type being eosinophil in 24%, neutrophil in 33%, macrophage in 22%, and mixed population of cells in 21%. Cultures for bacteria were considered positive in 24% of the cats. Circulating eosinophilia was not helpful in predicting the predominant cell type in bronchial cytologic exudates. Hyperproteinemia without dehydration was present in a third of the cats, indicating an immunologic response. Half the cats had resolution of clinical signs, whereas half the cats required continuing medication with bronchodilators, antimicrobial agents, or corticosteroids.

摘要

对65只患有支气管疾病的猫的病历、X光片和支气管细胞学异常情况进行了回顾。支气管疾病定义为下呼吸道异常,不包括起源于或主要累及肺泡、间质、脉管系统或胸膜的疾病。患有支气管疾病的猫更可能为雌性且年龄较大。暹罗猫的比例过高且患有更多慢性疾病。按出现频率排序,报告的临床症状如下:咳嗽、呼吸困难、偶尔打喷嚏、喘息和呕吐。X光检查显示支气管纹理增粗,部分猫出现右肺中叶萎陷(n = 7)、肺过度充气(n = 9)或吞气症(n = 13)。在65次支气管灌洗中,58次被认为是渗出性的,主要细胞类型为嗜酸性粒细胞的占24%;中性粒细胞占33%;巨噬细胞占22%;细胞混合群体占21%。24%的猫细菌培养呈阳性。循环嗜酸性粒细胞增多对预测支气管细胞学渗出物中的主要细胞类型并无帮助。三分之一的猫存在无脱水的高蛋白血症,表明有免疫反应。一半的猫临床症状得到缓解,而另一半的猫需要继续使用支气管扩张剂、抗菌药物或皮质类固醇进行治疗。

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