Bodem G, Boldt U, Ochs H
Klin Wochenschr. 1977 Apr 1;55(7):355-6. doi: 10.1007/BF01488117.
12 patients were treated for at least two days with digoxin or beta-methyldigoxin before a lumbar punction was done for diagnostic purposes. At the same time venous blood was drawn and both samples were radioimmunologically analysed for digoxin concentration. The relationship of concentrations from plasma to cerebrospinal fluid was 2 for beta-methyldigoxin and 8 for digoxin.
12名患者在进行腰椎穿刺以作诊断之前，接受了至少两天的地高辛或β-甲基地高辛治疗。与此同时，采集静脉血，并对两份样本进行放射免疫分析以测定地高辛浓度。β-甲基地高辛的血浆浓度与脑脊液浓度之比为2，地高辛则为8。
