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O-GLYCBASE:O-糖基化蛋白的修订数据库。

O-GLYCBASE: a revised database of O-glycosylated proteins.

作者信息

Hansen J E, Lund O, Nielsen J O, Hansen J E, Brunak S

机构信息

Laboratory for Infectious Diseases, University of Copenhagen, Denmark.

出版信息

Nucleic Acids Res. 1996 Jan 1;24(1):248-52. doi: 10.1093/nar/24.1.248.

Abstract

O-GLYCBASE is a comprehensive database of information on glycoproteins and their O-linked glycosylation sites. Entries are compiled and revised from the SWISS-PROT and PIR databases as well as directly from recently published reports. Nineteen percent of the entries extracted from the databases needed revision with respect to O-linked glycosylation. Entries include information about species, sequence, glycosylation site and glycan type, and are fully referenced. Sequence logos displaying the acceptor specificity for the GaINAc transferase are shown. A neural network method for prediction of mucin type O-glycosylation sites in mammalian glycoproteins exclusively from the primary sequence is made available by E-mail or WWW. The O-GLYCBASE database is also available electronically through our WWW server or by anonymous FTP.

摘要

O-GLYCBASE是一个关于糖蛋白及其O-连接糖基化位点的综合信息数据库。条目是从SWISS-PROT和PIR数据库以及直接从最近发表的报告中汇编和修订的。从数据库中提取的条目有19%在O-连接糖基化方面需要修订。条目包括有关物种、序列、糖基化位点和聚糖类型的信息,并提供了完整的参考文献。展示了针对GaINAc转移酶的受体特异性的序列标识。通过电子邮件或万维网提供了一种仅根据一级序列预测哺乳动物糖蛋白中粘蛋白型O-糖基化位点的神经网络方法。O-GLYCBASE数据库也可通过我们的万维网服务器或匿名文件传输协议以电子方式获取。

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