George D G, Dodson R J, Garavelli J S, Haft D H, Hunt L T, Marzec C R, Orcutt B C, Sidman K E, Srinivasarao G Y, Yeh L S, Arminski L M, Ledley R S, Tsugita A, Barker W C
National Biomedical Research Foundation (NBRF), Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20007, USA.
Nucleic Acids Res. 1997 Jan 1;25(1):24-8. doi: 10.1093/nar/25.1.24.
From its origin, the PIR has aspired to support research in computational biology and genomics through the compilation of a comprehensive, quality controlled and well-organized protein sequence information resource. The resource originated with the pioneering work of the late Margaret O. Dayhoff in the early 1960s. Since 1988, the Protein Sequence Database has been maintained collaboratively by PIR-International, an association of macromolecular sequence data collection centers dedicated to fostering international cooperation as an essential element in the development of scientific databases. The work of the resource is widely distributed and is available on the World Wide Web, via FTP, E-mail server, CD-ROM and magnetic media. It is widely redistributed and incorporated into many other protein sequence data compilations including SWISS-PROT and theEntrezsystem of the NCBI.
自成立以来,蛋白质信息资源库(PIR)一直致力于通过汇编全面、质量可控且组织有序的蛋白质序列信息资源,来支持计算生物学和基因组学研究。该资源起源于20世纪60年代初玛格丽特·O·戴霍夫(Margaret O. Dayhoff)的开创性工作。自1988年以来,蛋白质序列数据库由国际蛋白质信息资源库(PIR-International)合作维护,这是一个大分子序列数据收集中心协会,致力于促进国际合作,将其作为科学数据库发展的重要元素。该资源的工作广泛传播,可通过万维网、文件传输协议(FTP)、电子邮件服务器、光盘和磁介质获取。它被广泛重新分发并纳入许多其他蛋白质序列数据汇编中,包括SWISS-PROT和美国国立医学图书馆国家生物技术信息中心(NCBI)的Entrez系统。