EcoCyc：大肠杆菌基因与代谢百科全书。
EcoCyc: an encyclopedia of Escherichia coli genes and metabolism.
作者信息
Karp P D, Riley M, Paley S M, Pelligrini-Toole A
机构信息
Artificial Intelligence Center, SRI International, Menlo Park, CA 94025, USA.
出版信息
Nucleic Acids Res. 1996 Jan 1;24(1):32-9. doi: 10.1093/nar/24.1.32.
The encyclopedia of Escherichia coli genes and metabolism (EcoCyc) is a database that combines information about the genome and the intermediary metabolism of E.coli. It describes 2034 genes, 306 enzymes encoded by these genes, 580 metabolic reactions that occur in E.coli and the organization of these reactions into 100 metabolic pathways. The EcoCyc graphical user interface allows query and exploration of the EcoCyc database using visualization tools such as genomic map browsers and automatic layouts of metabolic pathways. EcoCyc spans the space from sequence to function to allow investigation of an unusually broad range of questions. EcoCyc can be thought of as both an electronic review article, because of its copious references to the primary literature, and as an in silico model of E.coli that can be probed and analyzed through computational means.
大肠杆菌基因与代谢百科全书（EcoCyc）是一个整合了大肠杆菌基因组信息和中间代谢信息的数据库。它描述了2034个基因、由这些基因编码的306种酶、大肠杆菌中发生的580种代谢反应以及这些反应如何组织成100条代谢途径。EcoCyc图形用户界面允许使用诸如基因组图谱浏览器和代谢途径自动布局等可视化工具来查询和探索EcoCyc数据库。EcoCyc跨越了从序列到功能的空间，以允许研究异常广泛的问题。由于EcoCyc大量引用了原始文献，它既可以被视为一篇电子综述文章，也可以被视为一个可以通过计算手段进行探测和分析的大肠杆菌计算机模型。
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