Braunstein R E, Jain S, McCally R L, Stark W J, Connolly P J, Azar D T
Wilmer Institute, Johns Hopkins University, Baltimore, MD, 21287-9233, USA.
Ophthalmology. 1996 Mar;103(3):439-43. doi: 10.1016/s0161-6420(96)30674-x.
To obtain objective measurements of corneal light scattering after excimer laser keratectomy, and to evaluate the relation of light scattering to clinical haze grading and visual acuity.
The authors measured best-corrected visual acuity, subjective clinical haze grade, and corneal light-scattering index in patients undergoing photorefractive keratectomy (PRK) (n=26), and phototherapeutic keratectomy (n=8), preoperatively and postoperatively at 1,3,6,9, and 12 months or later. Corneal light scattering was correlated with visual acuity and clinical haze grade.
Corneal light scattering increased after PRK and was reduced after phototherapeutic keratectomy. Corneal light scattering index showed a stronger positive correlation with logMAR visual acuity (r=0.57) than clinical haze grading (r=0.34). Corneal light-scattering index (P<0.05 at 1 and 3 months) and clinical haze grading (P<0.05 at 6, 9, and 12 months) were significantly higher in eyes undergoing PRK with ablation depths of more than 80 microns.
Excimer laser surgery affects corneal light scattering. Ablations with depths greater than 80 microns produce significantly higher levels of haze than those less than 80 microns. Objective measurement of corneal light scattering may be useful in monitoring the outcome of excimer keratectomy.
获得准分子激光角膜切削术后角膜光散射的客观测量值，并评估光散射与临床 haze 分级及视力的关系。
作者测量了接受准分子激光原位角膜磨镶术（PRK）（n = 26）和光治疗性角膜切削术（n = 8）的患者术前及术后 1、3、6、9 和 12 个月或更晚时间的最佳矫正视力、主观临床 haze 分级和角膜光散射指数。将角膜光散射与视力和临床 haze 分级进行相关性分析。
PRK 术后角膜光散射增加，光治疗性角膜切削术后角膜光散射降低。角膜光散射指数与 logMAR 视力的正相关性（r = 0.57）强于与临床 haze 分级的正相关性（r = 0.34）。消融深度超过 80 微米的 PRK 手术眼，其角膜光散射指数在 1 个月和 3 个月时（P < 0.05）以及临床 haze 分级在 6 个月、9 个月和 12 个月时（P < 0.05）均显著更高。
准分子激光手术会影响角膜光散射。消融深度大于 80 微米比小于 80 微米产生的 haze 水平显著更高。角膜光散射的客观测量可能有助于监测准分子激光角膜切削术的结果。
