Haapanen N, Miilunpalo S, Vuori I, Oja P, Pasanen M
UKK Institute for Health Promotion Research, Tampere, Finland.
Am J Epidemiol. 1996 May 1;143(9):870-80. doi: 10.1093/oxfordjournals.aje.a008830.
The association between leisure time physical activity and the risk of all-cause and cardiovascular disease mortality was analyzed in a Finnish cohort of 1,072 men age 35-63 years who were followed up for 10 years and 10 months. During the period, 168 deaths were recorded, 93 of which were the result of cardiovascular diseases. Leisure time physical activity was assessed by several measures: 1) a single question combining an estimate of the frequency and intensity of the total amount of leisure time physical activity, 2) a compiled measure of leisure time physical activity derived from three separate questions concerning the intensity and frequency of activity, 3) a physical energy expenditure index computed as an estimate of weekly energy expenditure for leisure time activity and commuting to work, 4) 16 separate specified activities of daily living and domestic chores included in the leisure time physical activity index. The association between baseline leisure time physical activity and the risk of death was assessed using the Cox proportional hazards model. After adjustment for potential confounders, the leisure time physical activity energy expenditure index and participation in several specific activities of daily living and domestic chores showed that the mortality risk for all causes and cardiovascular diseases was highest in the most sedentary men. With respect to the leisure time physical activity energy expenditure index, sedentary men ( those with an estimated weekly energy expenditure in leisure time physical activity of < 800 kcal) had an increased risk of 2.74 (95% confidence interval 1.46-5.14) for all-cause mortality and a risk of 3.58 (95% confidence interval 1.45-8.85) for cardiovascular disease mortality compared with the most active persons (those with an estimated weekly energy expenditure in leisure time physical activity of at least 2,100 kcal) when age, initial health status, marital status, employment status, and smoking were controlled.
在芬兰一个由1072名年龄在35至63岁之间的男性组成的队列中，分析了休闲时间体力活动与全因死亡率和心血管疾病死亡率风险之间的关联，该队列随访了10年零10个月。在此期间，记录了168例死亡病例，其中93例是心血管疾病导致的。休闲时间体力活动通过多种方式进行评估：1）一个单一问题，综合了对休闲时间体力活动总量的频率和强度的估计；2）一个综合的休闲时间体力活动测量值，源自关于活动强度和频率的三个单独问题；3）一个体力能量消耗指数，计算为休闲时间活动和通勤的每周能量消耗估计值；4）休闲时间体力活动指数中包含的16项单独的特定日常生活和家务活动。使用Cox比例风险模型评估基线休闲时间体力活动与死亡风险之间的关联。在对潜在混杂因素进行调整后，休闲时间体力活动能量消耗指数以及参与若干特定的日常生活和家务活动表明，久坐不动的男性全因死亡率和心血管疾病死亡率风险最高。就休闲时间体力活动能量消耗指数而言，在控制了年龄、初始健康状况、婚姻状况、就业状况和吸烟因素后，久坐不动的男性（休闲时间体力活动估计每周能量消耗<800千卡）全因死亡率风险增加2.74（95%置信区间1.46 - 5.14），心血管疾病死亡率风险增加3.58（95%置信区间1.45 - 8.85），而最活跃的人群（休闲时间体力活动估计每周能量消耗至少2100千卡）则不然。
