Macfarlane G J, Sharp L, Porter S, Franceschi S
ARC Epidemiology Research Unit, School of Epidemiology and Health Sciences, University of Manchester, UK.
Br J Cancer. 1996 Mar;73(6):805-8. doi: 10.1038/bjc.1996.141.
Data were examined to determine trends in survival from cancers of the oral cavity and pharynx in Scotland between 1968 and 1987, and to analyse survival rates and the previously noted increases in the incidence of such cancers according to the level of social deprivation. Incidence data on oral cavity and pharyngeal cancer and survival rates following diagnosis were obtained from the Information and Statistics Division of the Common Services Agency for the National Health Service in Scotland, covering the period 1968-92. It was found that survival rates for cancers of the tongue, mouth and pharynx diagnosed among persons less than 65 years of age decreased between 1968-72 and 1983-87. Five year relative survival rates fell from 47% to 39% over this period, while the equivalent rates among persons older than 65 years have shown a modest improvement from 34% to 38%. When considered by level of social deprivation, survival is lower among persons from the most deprived areas, and it is among such persons that the recent increases in occurrence of cancers of the oral cavity and pharynx have primarily occurred. The poorer survival among those from more socially deprived areas, and the evidence that the largest increase in incidence has occurred in such areas may to some extent explain the non-favourable trends in mortality. More importantly it emphasises the potential benefits of targeting such a population for oral health information. An educational campaign should include both information on the risk factors for developing oral cancer, and also the importance of seeking an early professional consultation in the case of symptoms.
对1968年至1987年间苏格兰口腔和咽喉癌的生存趋势进行了数据研究，并根据社会剥夺程度分析了生存率以及此前注意到的此类癌症发病率的上升情况。口腔和咽喉癌的发病率数据以及诊断后的生存率数据来自苏格兰国民保健服务公共服务局信息与统计司，涵盖1968 - 1992年期间。研究发现，1968 - 1972年至1983 - 1987年间，65岁以下人群中诊断出的舌癌、口腔癌和咽喉癌的生存率有所下降。在此期间，五年相对生存率从47%降至39%，而65岁以上人群的相应生存率则略有提高，从34%升至38%。按社会剥夺程度考量，最贫困地区人群的生存率较低，而且口腔和咽喉癌发病率近期的上升主要发生在这类人群中。社会剥夺程度较高地区人群生存率较低，以及发病率上升幅度最大的情况出现在这类地区的证据，在一定程度上可能解释了死亡率方面的不利趋势。更重要的是，这凸显了针对这类人群提供口腔健康信息的潜在益处。一场教育活动应既包括有关患口腔癌风险因素的信息，也包括出现症状时寻求早期专业咨询的重要性。
