Krakówka P, Korzeniewska-Koseła M, Halweg H, Bestry I
I Kliniki Gruźlicy i Chorób Płuc, Warszawie.
Pneumonol Pol. 1990 Nov-Dec;58(11-12):624-8.
A case report is presented of a 74 year old male with chronic bronchitis in whom fever, malaise and sputum hypersecretion was observed. Inflammatory changes in the right upper lobe were found on a chest radiogram. Broad spectrum antibiotics and antituberculous agents did not produce any improvement. Due to the fact that Aspergillus fumigatus organisms were cultured from the sputum and the precipitin test was positive to aspergillin the diagnosis of Aspergillus fumigatus infection was made. 5-fluorocytosine--Ancotil did not bring any improvement. After initiating steroid therapy with 30 mg of prednisone an improvement was observed. This allowed to diagnose hyperreactivity to Aspergillus fumigatus as the cause of the disease.
本文报告一例74岁男性慢性支气管炎患者，该患者出现发热、不适及痰液分泌过多症状。胸部X光片显示右上叶有炎症改变。使用广谱抗生素和抗结核药物治疗均未见改善。由于痰培养发现烟曲霉菌且曲霉菌沉淀素试验呈阳性，故诊断为烟曲霉菌感染。使用5-氟胞嘧啶 - 安可替治疗无效。在开始使用30毫克泼尼松进行类固醇治疗后，病情有所改善。据此诊断该病是由对烟曲霉菌的高反应性引起的。
