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[1986 - 1991年什切青地区人群狂犬病预防情况评估]

[Evaluation of rabies prophylaxis in people of the Szczecin region in the years 1986-1991].

作者信息

Majchrowicz H

机构信息

Katedry i Kliniki Chorób Zakaźnych Pomorskiej Akademii Medycznej w Szczecinie.

出版信息

Ann Acad Med Stetin. 1995;41:171-82.

PMID:8615542
Abstract

UNLABELLED

The aim of the study was the analysis of epizootic and epidemiological situation of rabies in the region of Pomerania in 1986-1991 and the evaluation of correctness in determining indications for antirabies vaccination. In analysed period of time 441 cases of rabies in domestic and wild animals were noted. Altogether 2941 subjects were admitted to the Rabies Prophylaxis Outpatient Center (Fig. 1, Tab 1-7). Indications for vaccination were analysed in each case as well as the possibility to reduce the number of vaccinated patients in respect of economical benefits was considered. Vaccinated patients were inquired about side effects of Human Diploid Cell Vaccine (HDCV) (Merieux France). Among 2941 patients admitted to the out-patient clinic indications for rabies vaccination were given in 933 cases (31.7%). Most often they were determined due to dogs bite or another contact with dog's saliva. Postvaccinal reactions were observed in 61 cases (6.5%), mostly topical ones. Neurological complications were not noticed.

CONCLUSIONS

  1. Despite the fact that the epizootic situation in domestic and wild animals has changed for worse, the number of indications for prophylactic vaccination decreased in last six years. 2. Proper evaluation of the indications for prophylactic vaccinations against rabies is the most important factor influencing the reduction in the number of vaccinated people. 3. Rationalisation of indications for vaccination against rabies justified claims to be economical one. 4. HDCV (Merieux) is a safe vaccine and its usage reduced the side effects to minimum degree.
摘要

未标注

本研究的目的是分析1986 - 1991年波美拉尼亚地区狂犬病的流行情况和流行病学状况,并评估确定狂犬病疫苗接种指征的正确性。在分析时间段内,记录到家养和野生动物的441例狂犬病病例。共有2941名受试者前往狂犬病预防门诊中心就诊(图1,表1 - 7)。分析了每例的疫苗接种指征,并考虑了从经济效益角度减少接种患者数量的可能性。询问了接种患者关于人二倍体细胞狂犬病疫苗(HDCV,法国梅里埃公司生产)的副作用情况。在前往门诊就诊的2941例患者中,933例(31.7%)有狂犬病疫苗接种指征。最常见的是因被狗咬伤或与狗的唾液有其他接触而确定接种指征。观察到61例(6.5%)有接种后反应,大多为局部反应。未发现神经并发症。

结论

  1. 尽管家养和野生动物的流行情况恶化,但在过去六年中预防性疫苗接种指征的数量有所下降。2. 正确评估狂犬病预防性疫苗接种指征是影响接种人数减少的最重要因素。3. 狂犬病疫苗接种指征的合理化证明其在经济方面是合理的。4. HDCV(法国梅里埃公司生产)是一种安全的疫苗,其使用将副作用降至最低程度。

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