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失语症的恢复模式与预后

Recovery patterns and prognosis in aphasia.

作者信息

Kertesz A, McCabe P

出版信息

Brain. 1977 Mar;100 Pt 1:1-18. doi: 10.1093/brain/100.1.1.

Abstract

Ninety-three aphasics were studied with repeated language assessment by a scorable test (the Western Aphasia Battery). Recovery rates were determined by measuring language performance (Aphasia Quotient) at nought to forty-five days post-onset, and three, six and twelve months and yearly after. Recovery rates were higher in post-traumatic than in cerebrovascular cases. When the stable infarcts were separately studied, the greatest recovery was seen in "Broca's" aphasics, followed by the "conduction" group. Anomic aphasia appeared to be a common end-stage of evolution. Long-term follow-up (twelve months or more) demonstrated that global aphasics have a poor prognosis, while Broca's and Wernicke's have an intermediate one. Complete recovery occurred frequently among anomic, conduction and transcortical aphasics and in more than half of the traumatic cases. Initial severity and outcome correlated significantly. Age and rate of initial recovery showed a trend of negative correlation; younger patients recovered better, but there were frequent exceptions, depending on other factors, such as the initial severity of aphasia. Although some cases recovered exceptionally well while under therapy, there was no significant difference between the treated and untreated groups, where such a comparison was possible.

摘要

对93名失语症患者进行了研究,通过一项可评分测试(西方失语症成套测验)进行重复的语言评估。恢复率通过测量发病后0至45天、3个月、6个月、12个月及之后每年的语言表现(失语症商数)来确定。创伤性病例的恢复率高于脑血管病例。当对稳定梗死病例单独研究时,“布罗卡区”失语症患者恢复程度最大,其次是“传导性”失语症组。命名性失语似乎是常见的终末期演变类型。长期随访(12个月或更长时间)表明,完全性失语症患者预后较差,而布罗卡区失语症和韦尼克区失语症患者预后中等。命名性、传导性和经皮质性失语症患者以及半数以上的创伤性病例中经常出现完全恢复的情况。初始严重程度与预后显著相关。年龄与初始恢复率呈负相关趋势;年轻患者恢复较好,但也有很多例外情况,这取决于其他因素,如失语症的初始严重程度。尽管有些病例在治疗期间恢复得非常好,但在可以进行此类比较的治疗组和未治疗组之间没有显著差异。

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