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卡利曼塔星A、B和C,来自产碱杆菌属菌株YL-02632S的新型抗生素。I. 分类学、发酵、分离及生物学特性

Kalimantacins A, B and C, novel antibiotics from Alcaligenes sp. YL-02632S. I. Taxonomy, fermentation, isolation and biological properties.

作者信息

Kamigiri K, Suzuki Y, Shibazaki M, Morioka M, Suzuki K, Tokunaga T, Setiawan B, Rantiatmodjo R M

机构信息

Yamanouchi Pharmaceutical Co., Ltd., Tokyo, Japan.

出版信息

J Antibiot (Tokyo). 1996 Feb;49(2):136-9. doi: 10.7164/antibiotics.49.136.

DOI:10.7164/antibiotics.49.136
PMID:8621352
Abstract

Novel antibacterial antibiotics, kalimantacins A, B and C, have been isolated from the fermentation broth of Alcaligenes sp. YL-02632S. In this paper, the taxonomy of the producing strain, fermentation, isolation and biological activities of kalimantacins are reported. Kalimantacins inhibit the growth of Staphylococcus aureus and S. epidermidis including multiple-drug resistant strains.

摘要

新型抗菌抗生素卡里曼他辛A、B和C已从产碱杆菌属菌株YL-02632S的发酵液中分离出来。本文报道了产生该抗生素的菌株的分类学、发酵、分离及卡里曼他辛的生物活性。卡里曼他辛可抑制金黄色葡萄球菌和表皮葡萄球菌的生长,包括多重耐药菌株。

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