Chan M K, Lau K M, Tsui Y, Wong F W, Huang D P
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong.
Gynecol Oncol. 1996 Feb;60(2):217-23. doi: 10.1006/gyno.1996.0028.
Detection of human papillomavirus (HPV) was accomplished by utilizing polymerase chain reaction methods on cervical scrapes from a total of 488 Hong Kong Chinese women attending the colposcopy, general, and antenatal clinics. From colposcopy clinic, 10% of normal cervix, 31% of condyloma, 56, 50, and 57% of CIN I, CIN II, and CIN III, respectively, and 88% of squamous cell carcinoma contain HPV. The overall detection rate is 30%. The most prevalent type is 16. Four percent of scrapes from normal cervix of patients attending general gynecology clinic and none from antenatal clinic show HPV. The detection rate appears to be more related to the types of cervical lesions than to the age of the patients.
通过聚合酶链反应方法，对488名前往阴道镜检查诊所、普通诊所和产前诊所就诊的中国香港女性的宫颈刮片进行检测，以检测人乳头瘤病毒（HPV）。在阴道镜检查诊所中，正常宫颈中有10%、尖锐湿疣中有31%、CIN I中有56%、CIN II中有50%、CIN III中有57%以及鳞状细胞癌中有88%含有HPV。总体检出率为30%。最常见的类型是16型。在普通妇科诊所就诊患者的正常宫颈刮片中，有4%显示感染HPV，而在产前诊所就诊患者的宫颈刮片中未检测到HPV。检出率似乎与宫颈病变类型的关系更大，而非与患者年龄相关。
